Calorie Restriction Results in Fat Burning

Craig's Avatar


16 Jul, 2012 09:18 AM

I found this study interesting. These calorie restricted mice are actually creating fat just to turn around and burn it.

"CR mice oxidized four times as much fat per day as ad libitum (AL)-fed controls (367 +/- 19 vs. 97 +/- 14 mg/day, P < 0.001) despite reduced energy intake from fat. This increase in FA oxidation was balanced by a threefold increase in adipose tissue FA synthesis compared with AL. Expression of FA synthase and acetyl-CoA carboxylase mRNA were increased in adipose and liver in a time-dependent manner. We conclude that CR induces a surprising metabolic pattern characterized by periods of elevated FA synthesis alternating with periods of FA oxidation disproportionate to dietary FA intake. This pattern may have implications for oxidative damage and disease risk."

You've gotta love that last lipophobic line! Fat burning is probably THE major reason CR extends life.

  1. Support Staff 1 Posted by Fiona on 25 Jul, 2012 04:47 PM

    Fiona's Avatar

    It is quite amazing, all the studies that prove that being a fat burner truly is the answer, yet it is still not the standard of practice in our health care system.

    Best of health!

  2. 2 Posted by FreeSoftware on 24 Aug, 2015 03:54 PM

    FreeSoftware's Avatar

    Aside from weight loss, if you are concerned about getting into the fat burning mode for other health benefits , then ingesting carbohydrate calories breaks the fast, so your juice will stop any progress you might make toward that goal.

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